I've been messing with Painter lately. This is the final of the Iron Man I posted a few days ago.
I haven't painted since colleg and it was never my media of choice, but I really enjoyed messing with this. Once I got the hang of how you get the paint to blend.
Painter seems to replicate the painting experience pretty good, except for no painting brushes or no smell.
Cleaning the brushes I didn't miss, but to be honest the smell of paints I did miss. It always made everything seem more 'arty.'
Btw, I didn't paint the background, it's a photo I swiped off the web.